|
Triglycerides measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
|
Systolic Pressure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Squamous cell carcinoma
|
|
0.700 |
GeneticVariation
|
GWASDB |
Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.
|
23103227 |
2012 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Whole genome sequencing and imputation in isolated populations identify genetic associations with medically-relevant complex traits.
|
28548082 |
2017 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
|
24023260 |
2013 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic association with lipids in Filipinos: waist circumference modifies an APOA5 effect on triglyceride levels.
|
24023260 |
2013 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa.
|
31675503 |
2019 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.
|
28270201 |
2017 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels.
|
28334899 |
2017 |
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE.
|
23067351 |
2012 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
Serum LDL cholesterol measurement
|
|
0.700 |
GeneticVariation
|
GWASDB |
Impact of common genetic variation on response to simvastatin therapy among 18 705 participants in the Heart Protection Study.
|
23100282 |
2013 |
|
Reticulocyte count (procedure)
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
response to statin
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.
|
22331829 |
2012 |
|
Red cell distribution width determination
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
Red cell distribution width determination
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Red Blood Cell Count measurement
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
RDW - Red blood cell distribution width result
|
|
0.700 |
GeneticVariation
|
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
RDW - Red blood cell distribution width result
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
Presenile dementia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We reach four principal conclusion from this study: 1) rs429358 alone is responsible for the association of APOE with dementia; 2) The association of APOE with dementia is substantially mediated by its effect on CNS Aß42 levels; 3) The association of APOE with dementia is not mediated by its impact on peripheral lipid metabolism; and 4) The dichotomy of effects of rs429358 and rs7412 represents one of the best examples of genetic pleiotropy for complex traits known and illustrates the importance of allelic heterogeneity in APOE.
|
20847432 |
2010 |